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Comparing and Contrasting T3 and T4:
T3 and T4, as mentioned in this study which references the 1999 publication of the British National Formulary states that 10mcg of T3 (as linthyronine) is bioequivalnet to 50mcg T4 (as levothyroxine).
- Against Each other
The fat loss effects of T3 supplementation appear to be more effective than T4 supplementation at weight loss, although studied in hypothyroidics and dosed in accordance to TSH levels, at an average dose of 0.57mcg/kg bodyweight.
- In conjunction with each other
The combination of T3/T4 (in which 50mcg of T4 was exchanged for 10mcg T3) in comparison to straight T4 supplementation had no significant differences in term of subjective well-being and treatment of hypothyroidism. and similar lack of results seen with a higher dose substitution and lower doses. These results are in contrast to an earlier study which showed benefit substituting 50mcg T4 for 12.5mcg T3 which appears to stand alone.
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